Vital 3

Vital 3 is an anti-inflammatory joint supplement. Its main goal is to diminish the pain, stiffness, and loss of mobility associated with arthritis and other forms of joint inflammation. But can it really?

According to the official website,, Vital 3 has been rigorously tested in 10 human clinical trials. Based on the results of these trials, Vital 3 was proven to be safe and extremely effective.

However, official websites are by definition biased. So I gathered all the research to see what Vital 3 could really do.

Ingredient Research

Although it was difficult to locate the ingredient list, I obtained it by contacting customer service. I found Vital 3 has 1 active ingredient: Type-II Collagen. Beyond that, it contains distilled water and acetic acid—a natural preservative.

Type-II Collagen
Collagen is a protein which makes up a significant portion of cartilage. Type-II Collagen is roughly 50% of the protein in cartilage. Cartilage protects the joint from wear and tear and allows it to be strong and flexible at the same time.

But, is Type-II Collagen an effective anti-inflammatory? Studies done on Type-II Collagen show a decrease in swelling and fewer reports of pain in test subjects who were administered Type-II Collagen orally. [1]

Reducing inflammation in the joint not only decreases the painful symptoms of inflammation, but could prevent irreversible damage to the bones and joint structure resulting from destroyed cartilage. [1]

Clinical Trials

Vital 3’s official website claims Vital 3’s effectiveness is proven in 10 human clinical trials. There are 3 links listed on the website for different studies, but they all direct you to the same study.

I was able to find a couple other studies pertaining to Type-II Collagen, but not 10. It is always unsettling to see instances of exaggeration or deceit from a company.

However, the trials I found showed promising results. One study published in the International Journal of Medical Science tested the efficacy of treatment with Type-II Collagen versus treatment with glucosamine and chondroitin for arthritis in the knee. After 90 days, Type-II Collagen was significantly more effective. [2]

Another study published in Arthritis Rheum also showed how treatment with oral doses of Type-II Collagen for 12 weeks was significantly more effective than treatment with a placebo. [3]

Although I could not find proof of the 10 human clinical trials spoken of, Vital 3’s claims are nevertheless founded.

Usage Instructions

Vital 3 is a liquid supplement intended to be added to water or juice. Directions state the proper and effective dose for Vital 3 is 3 drops per day. Each bottle should last about six weeks.

Potential Side Effects

There were no adverse side effects reported in any trials done on Type-II Collagen. Users need not be concerned about drug interactions either.


Vital 3 is sold by and (manufacturer’s website) at the following prices.
• 1 bottle (6 week supply): $38.99 + $4.95 shipping
• 2 bottles (12 week supply): $75.98 +$4.95 shipping
• 3 bottles (18 week supply): $101.90 + $4.95 shipping
• Automatic product shipment: $68.58 +free shipping. For this option, you will automatically receive 2 bottles of Vital 3 every three months. Re-ordering is unnecessary since they automatically charge your credit card.

As you can see, the automatic shipment option is the best deal. Bronson Laboratories’ return policy, which applies to both websites, is very flexible. You have a one year window from the date of purchase to return Vital 3. Simply follow the instructions outlined on their website and mail back the unused portion of the product.


Vital 3 seems like an easy to use, risk free, and effective supplement. It is reasonably priced and sold by a company who seems to be confident in their product based on their return policy.

Although Vital 3 makes unsubstantiated claims about having 10 human clinical trials to back up their product, it still seems to be an effective joint supplement. The clinical trials I did find backed up the claims that Vital 3 would reduce pain, stiffness, and mobility problems.

Customers on and rated Vital 3 very positively. I would recommend Vital 3 to those who are looking for a non-prescription joint supplement that is effective and natural.


[1] Trentham, David E., Roselynn A. Dynesius-Trentham, and E. John Orav. “Effects of Oral Administration of Type-II Collagen on Rheumatoid Arthritis.” Science 261 (1993): 1727-730. The American Association for the Advancement of Science. Web. 3 Dec. 2012. .

[2] Crowley, D. C., F. C. Lau, and P. Sharma. “Safety and Efficacy of Undenatured Type II Collagen in the Treatment of Osteoarthritis of the Knee: A Clinical Trial.” National Center for Biotechnology Information. U.S. National Library of Medicine, n.d. Web. 03 Dec. 2012. .

[3] Barnett, M. L., J. M. Kremer, and E. W. St. Clair. “Treatment of Rheumatoid Arthritis with Oral Type II Collagen. Results of a Multicenter, Double-blind, Placebo-controlled Trial.” National Center for Biotechnology Information. U.S. National Library of Medicine, 4 Feb. 1998. Web. 03 Dec. 2012. .

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