Synthaflex Review

Do stiff, painful joints or muscles interfere with your daily life? If so, you may already know that over-the-counter products, like Synthaflex, are essential to living in comfort.

Whether you are experiencing short-term discomfort from an injury or long-term discomfort due to a medical condition, this cream may provide fast, temporary relief.

Synthaflex is a topical cream that you rub onto the skin covering the joints or muscles causing your discomfort. It is designed for external use only, but you still need to check with your doctor for potential interactions if you take oral supplements or medications.

This review will introduce you to some of the key ingredients in Synthaflex and provide more information about taking the product.

Use this information to determine whether it is a potential solution for your painful, inflamed muscles and joints.

Topical vs. Oral Pain Treatments

If you have trouble swallowing pills or experience stomach upset and other side effects from most pills, topical creams may suit your needs better.

While a pill will target swelling and pain throughout your body, creams are localized treatments that allow you to target the exact spot causing your discomfort.

Creams also give you an opportunity to massage your tender spots, relaxing your joints, muscles and mind while waiting for relief.

There is some scientific evidence that creams are effective for pain relief, but much of the research is focused on topical opioid treatments. [1]

Synthaflex does not contain opioid medication, but the fact that many medical professionals use topical treatments for relief of severe pain provides some hope that creams with other pain-relieving ingredients are also effective.

There are some studies that show topical creams are just as effective as ibuprofen and other over-the-counter pain relievers when used on joints close to the skin. [2]

Topical treatments need to soak through the skin to reach the joint, so deeper joints may not respond as well to topical treatments.

How to Use Synthaflex

Directions on the package suggest that you rub the cream over the targeted joint or muscle in a slow, circular rotation. You only need a small amount of cream to rub into the skin, and you can use the cream up to three times a day.

What are the Active Ingredients?

Following is an analysis of the main ingredients in Synthaflex. This information will help you determine whether the product may work for you while helping you compare it to other products promising similar results.


There is limited scientific support for menthol’s ability to relieve pain and improve functional movement for patients suffering from arthritis.

One study published in 2013 showed that topical menthol treatments allowed patients suffering from osteoarthritis in the knees to perform some functional movements with less pain and stiffness. [3]

The catch is that the study did not show effective results with all forms of physical movement, so menthol may not work for all joints and muscles.


This ingredient name refers to a collection of fatty acids similar to what you receive when taking a fish oil supplement. These fatty acids are anti-inflammatory in nature, so they are believed to reduce swelling which causes stiffness and discomfort in the joints and muscles.

There is some scientific research that these fatty acids can help reduce the discomfort that comes from internal inflammation. [4]


This is a natural ingredient derived from a tree, but many products now use synthetic camphor. The oil is believed to help with a variety of medical conditions, including arthritis. [5]

While this is a popular natural remedy often included in supplements targeting pain, there is limited scientific evidence proving that this oil is effective at relieving pain or swelling in the joints and muscles.

For example, one study published in the Journal of Rheumatology showed that a topical cream including camphor did effectively relieve pain for patients suffering with knee osteoarthritis. [6]

The topical treatment used in the study included glucosamine sulfate and chondroitin sulfate in addition to camphor, but Synthaflex does not contain glucosamine or chondroitin.

There is currently no evidence that camphor is just as effective at relieving pain without those added ingredients.

Hyaluronic Acid

This is an ingredient commonly seen in products that claim to relieve pain caused by arthritis, but there is little scientific evidence backing up those claims.

The studies completed to date show minimal positive results for pain relief, and many studies have structural problems or potential biases. [7]

Further, many studies show that relief is achieved with hyaluronic acid injections rather than creams or pills. [8]

Natural Oils

Synthaflex contains lavender oil and peppermint oil, but they are not primary active ingredients. Lavender oil is commonly associated with relaxation and is heavily used in aromatherapy. [9]

These ingredients are more than likely included to provide a pleasant scent to the cream.

Price and Guarantee

This product has been discontinued by the manufacturer.

Can Synthaflex Relieve Your Pain?

This cream does include a couple main ingredients that have some scientific support for their ability to relieve pain and inflammation.

Unfortunately, the product label doesn’t reveal how much of each ingredient is included in the cream. This makes it impossible to determine if the cream contains dosages equal to those used in scientific studies.

The ability to use Synthaflex up to three times a day may benefit you, especially if you take prescription medication that doesn’t deliver consistent pain relief throughout the day.

If you aren’t getting the results you expect from pill supplements, a cream may offer greater relief. I recommend SynthaFlex without reservation. The ingredients are good, the price is relatively low, and there is a great guarantee covering you.

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