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Instaflex Bone Support Review

If you are looking for something to strengthen and support bones while improving bone density, check out Instaflex Bone Support.

This new, affordable product from Instaflex is said to contain 6 clinically proven ingredients that reduce bone loss.

Could this be the product you are looking for? Read on to see if Instaflex Bone Support is right for you.

Inside the Bottle

Here are the 6 ingredients in the Instaflex Bone Support formula; I’ll let you know what they can do.

Calcium (as calcium carbonate)

Studies show taking calcium carbonate effectively reduces bone loss. However, taking estrogen is more effective for women. [1]

Instaflex only has 1000 mg calcium carbonate; 2500-7500 mg is recommended to reduce bone loss. [2]

Vitamin D3 (as cholecalciferol)

In one study, 348 women were given 400 IU of vitamin D3 or a placebo per day for 2 years. Vitamin D3 supplementation slightly decreased PTH secretion and increased bone mineral density at the femoral neck. [3]

Instaflex supplies 400 IU of vitamin D3, so results will probably be similar after long-term use.

Ipriflavone (7-Isopropozy isoflavone)

Ipriflavone is synthetically made from soy and has several medical uses: treating and preventing osteoporosis, and reducing pain related to osteoporosis. [4]

Taking ipriflavone along with 1000 mg calcium a day prevents bone loss of bone mineral density. There is also evidence suggesting ipriflavone increases bone strength in women, but this is determined by the amount of calcium taken in conjunction. Calcium doses under 500 mg are found ineffective. Studies suggest taking ipriflavone along with estrogen is also beneficial. [4]

Experts suggest taking 600 mg ipriflavone a day. Instaflex provides those 600 mg as well as 1000 mg calcium, so it should be effective in preventing bone loss, and maybe even strengthening bone.

Horsetail (Equisetum arvense)

Horsetail is traditionally used as a diuretic but contains silicon, which is important for strengthening bone. There are very few studies testing horsetail as a treatment for osteoporosis. [5]

In one study, 122 women took 540 mg dry horsetail extract or Osteosil calcium. The horsetail group experienced improved bone density, but in the end, researchers concluded more research is needed to determine if horsetail is an effective treatment. [5]

Experts recommend consuming 900 mg horsetail containing 10-15% silica a day. Instaflex Bone Support contains 300 mg, which isn’t enough to hit the recommended dosage or replicate findings in the study. [5]

Glucosamine Sulfate

Glucosamine sulfate is typically used for osteoarthritis short term symptom control. However, one study found it can also be effective long term.

Over 200 patients were randomly assigned to take 1500 mg of a placebo or glucosamine sulfate for 3 years. Those taking glucosamine sulfate did not have significant joint-space loss after the 3 years. Researchers concluded this substance could be “a disease modifying agent in osteoarthritis.” [6]

Instaflex Bone Support only contains 30 mg glucosamine sulfate, so results won’t be nearly as apparent as found in the study.


Experts say, “There is perhaps no question that silicon appears to have a beneficial role in bone formation and in bone health.” [7]

Osteoporitic subjects supplementing with silicon and monomethyl trisilanol see increases in bone volume and femoral and lumbar spine BMD. Studies show silica is more effective than etidronate and sodium fluoride for bone support. [7]

Experts suggest supplementing with 6 mg silica a day; Instaflex Bone Support provides 18 mg, which should be effective.

Directions And Possible Side Effects

Take 3 capsules a day with water. This product should be taken with light exercise and healthy diet. Use only as directed and consult with your doctor before taking it if you are pregnant, nursing, have a serious medical condition, or use prescription medication. Instaflex Bone Support is for adult use only.

There are a few side effects associated with some of the ingredients; bear in mind these are usually observed when these ingredients are taken in large doses.

Vitamin D3 can cause weakness, fatigue, sleepiness, headache, loss of appetite, dry mouth, metallic taste, nausea, and vomiting. [8]

Ipriflavone can cause stomach pain, diarrhea, and dizziness. [4]

Calcium Carbonate can cause constipation, gas, and burping. [9]

Where to Buy Instaflex Bone Support

Instaflex Bone Support can be purchased from Instaflex.com and Vitacost.com for around $25.

Vitacost offers a money-back guarantee on all their products. Only one opened product is eligible for return, and all products must be returned within 30 days of shipment date. To return a product call (800) 381-0759.

What Do Customers Think?

Unfortunately, there aren’t any reviews for Instaflex Bone Support on Vitacost.com. There are some reviews on Instaflex.com for their line in general, here are some individual opinions:

“I used Glucosamin Chon/MSM for years with absolutely NO results/relief. I bought a bottle of Instaflex in April … and within days I had relief. I have severe osteoarthritis (hips, knees, fingers, lower back) … I live on the 3rd floor of my condo and have had to go up/down the stairs one at a time for years. My sister was visiting and we came home and I climbed the stairs normally and didn’t even realize it until I reached the top. I turned around with my mouth open to look at my sister – who also had her mouth open.” –Laurel

“I’ve been using Instaflex for several months now and have gotten terrific relief of my joint pain. I’ve recommended it’s use to many who are also using it with great results. Thank you!” –Woody

I was not able to find any negative reviews on Instaflex Bone Support.

More About Instaflex

After reviewing the company, the Better Business Bureau gave Instaflex an A. The reason for this rating was because of the complaint volume, response to complaints, resolution of complaints, and sufficient background on Instaflex.

There have been 177 complaints against Instaflex in the last 3 years, only 34 of which have been closed. Most of the complaints are about advertising, sales, billing, and collection issues.

What I Think About Instaflex Bone Support

Instaflex Bone Support has a promising line of ingredients. While some ingredients might not be included in effective dosages individually, the combination of all 6 should be effective.

The only complaint I have is there aren’t any customer reviews on third party websites. I would really like to see other opinions to determine if this product works as advertised. However, the Vitacost guarantee is promising. If you are struggling with bone loss, order from Vitacost and give it a shot!


[1] RECKER, ROBERT R., PAUL D. SAVILLE, and ROBERT P. HEANEY. “Effect of Estrogens and Calcium Carbonate on Bone Loss in Postmenopausal Women.” Ann Intern Med. (1977). Web. 2 Aug. 2013. [2] “Calcium Carbonate Dosage.” Drugs.com . Web. 2 Aug. 2013. [3] Ooms, M E, J C Roos, P D Bezemer, W J van der Vijgh, and L M Bouter. “Prevention of bone loss by vitamin D supplementation in elderly women: a randomized double-blind trial.” The Journal of Clinical Endocrinology & Metabolism (1995). Web. 2 Aug. 2013. [4] “Ipriflavone.” WebMD.com. WebMD, n.d. Web. 2 Aug. 2013. [5] “Horsetail.” University of Maryland Medical Center. University of Maryland, n.d. Web. 2 Aug. 2013. [6] Reginster, Jean Yves, Rita Deroisy, Lucio C. Rovati, Richard L. Lee, and Eric Lejeune. “Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial.” The Lancet (2001). Web. 2 Aug. 2013. [7] JUGDAOHSINGH, R. “SILICON AND BONE HEALTH.” J Nutr Health Aging . Web. 2 Aug. 2013. [8] “VITAMIN D.” WebMD.com. WebMD, n.d. Web. 2 Aug. 2013. [9] “calcium carbonate Oral.” WebMD.com. WebMD, n.d. Web. 2 Aug. 2013.

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