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Cosamin ASU Review

Sometimes a “new and improved” formula is not always better than the original. Cosamin ASU is a maximum strength joint supplement produced by Nutramax Laboratories based on their best-selling product, Cosamin DS. Cosamin ASU uses the same tried and true glucosamine and chondroitin formula included in Cosamin DS with the addition of avocado/soybean unsaponifiables.

The ingredients in Cosamin ASU are supposed to better inhibit cartilage degradation and reduce inflammation. It is marketed as the most potent joint supplement available and the number one doctor recommended brand.
So, does Cosamin ASU live up to its claims? I researched Cosamin ASU to find out if it really is more effective than the trusted Cosamin DS.


Cosamin ASU has the same patented blend of Glucosamine and Chondroitin featured in Cosamin DS. But it contains the new ingredients Avocado and Soybean Unsaponifiables.

Glucosamine HCL: Glucosamine is used to cushion and support the joints. It inhibits cartilage breakdown when used in combination with chondroitin sulfate.

Chondroitin Sulfate: Chondroitin is a cartilage building block. It rebuilds and repairs damaged cartilage in joints.

Avocado/Soybean Unsaponifiables (ASU): Scientifically proven to reduce pain and inflammation in the joints, these new ingredients are certainly promising. In one study, ASU reduced the need for non-steroidal anti-inflammatory drugs (NSAIDs) after six weeks of use when compared to a placebo. [1]

Green Tea Leaf Extract: Green tea reduces inflammation by inhibiting chemokine production. Chemokines are signals in the body that promote inflammation.


Cosamin ASU and all products developed by Nutramax Laboratories are NSF certified. NSF is a national public health and safety foundation, dedicated to ensuring products are safe and effective. They offer free testing for good manufacturing practice and good laboratory practice.

Glucosamine can cause allergies because it is sometimes made from shellfish. It has also been known to cause gastrointestinal discomfort and headaches. However, those side effects are rare.

Chondroitin may also irritate some allergies, but has rarely been associated with adverse effects.
Overall, consumers should feel confident Cosamin ASU is safe.


Each Cosamin ASU serving (4 pills) contains 1500 mg of glucosamine HCL, 800 mg of chondroitin sulfate, and 400 mg of ASU. The recommended dosage for glucosamine HCL is 500 mg 3 times a day or 1500 mg once a day. The recommended dosage for chondroitin sulfate is 800-1200 mg/day. Cosamin ASU contains the most effective doses for both ingredients.

Avocado/soybean unsaponifiables were clinically tested for their effects on arthritis. Patients in several studies were given 300 mg ASU or a placebo. When ASU was clinically tested, it decreased the painful symptoms associated with arthritis. In addition, ASU reduced the need to take NSAIDs such as ibuprofen for pain. Since NSAIDS can eventually cause damage to the stomach and intestines, this eliminates future health risks. [1][2]

Customer Reviews

Cosamin ASU has extremely positive customer reviews. Despite the expensive price tag, Cosamin ASU has received numerous 5 star ratings on a variety of websites.

One Amazon.com customer, username SeaKayaker, stated that he started taking Cosamin ASU after his doctor recommended it to him. Several other customers also mentioned a doctors’ recommendation.

One customer on Amazon.com, username OnAJourney, said the person who recommended Cosamin ASU to him has been able to put off knee replacement surgery because of Coasmin ASU. Others stated that they felt the new formula was more effective than the original Cosamin DS.

Although almost all the reviews on Amazon.com were positive, many customers mentioned they felt Cosamin ASU is expensive.

There was only one negative review of Cosamin ASU on Amazon.com. Allan H. Grant wrote on his patient’s behalf and stated the product did not work for her. He feared the arthritis his patient was experiencing was too severe for anything to really affect it. He still recommended trying Cosamin ASU, however.

Where to Buy Cosamin ASU

Cosamin ASU is available at almost all drug stores including Rite Aid, BJ’s, Harmons, CVS, Publix, Walgreens, and Kroger stores. It is also available online from retailers such as Amazon.com, Costco.com, DrugStore.com, LuckyVitamin.com, and of course, NutramaxStore.com (manufacturer’s website).

Cosamin ASU is sold in 180 capsule bottles and the serving size is 4 pills/day. At this dosage, a 180 ct. bottle should last about 45 days.

Here are a few of the lowest online prices:

• NutramaxStore.com: $59.99
• Costco.com: $44.99
• DrugStore.com: $47.99
• Amazon.com: $49.99

In Conclusion

Although some customers feel that Cosamin ASU is expensive, especially if purchased from the manufacturer’s website, I believe it is effective and worth trying. It also lasts at least 45 days if the maximum dose is taken, but could last longer if a smaller dose is taken. It is easy to find as it is available in many stores. Furthermore, Cosamin ASU has extremely positive customer reviews.

Scientific evidence backs up every one of Cosamin ASU’s ingredients. All the ingredients are natural and it uses the most effective dosages. Cosamin ASU is likely more effective than its predecessor Cosamin DS, and is doctor recommended as we found out from customer reviews.

Customers should feel confident trying this product knowing it is safe and effective for treating joint pain.


[1] Blotman, F., and E. Maheu. “Efficacy and Safety of Avocado/soybean Unsaponifiables in the Treatment of Symptomatic Osteoarthritis of the Knee and Hip.” Rev Rheum Engl Ed.64.12 (1997): 825-34. National Center for Biotechnology Information. U.S. National Library of Medicine. Web. 12 Dec. 2012. .

[2] Christensen, R., and E. M. Bartels. “Symptomatic Efficacy of Avocado-soybean Unsaponifiables (ASU) in Osteoarthritis (OA) Patients: A Meta-analysis of Randomized Controlled Trials.” Oseoarthritis Cartilage 16.4 (2008): 399-408.National Center for Biotechnology Information. U.S. National Library of Medicine, 26 Nov. 2007. Web. 12 Dec. 2012. .

Cosamin ASU User Reviews

1 Review  | Write a Review

  1. Comment

    My mother has been having knee pain for a while, then a friend not only recommended but bought her a COSAMIN ASU
    and in less than a month she star filling better, her joint did not hurts like they did before, I will recommend this pills, and I found this pills at Walmart on a 60 count for only 21.99 thanks Nutramax laboratories.

    Bety Rios
    March 3, 2013 at 9:41 pm

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